Generalized lichen planus...what should be the treatment strategy?
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Oral Lichen planus. The patient had extensive areas of skin, mucosa and nails involved. An increasing number of generalized LP cases is being reported. I usually ask for anti HCV, but it turns out to be positive in only a few cases. What would be the preferred treatment option for such florid cases? View Images
3 Comments:
Dr.Amor Khachemoune,MD, CWS responded,
Tacrolimus in some oral preparation has been reported to help. Amor
11:18 PM
Dr.Jose Catacora from Lima Peru respoded,
For skin and nail lichen planus acitretin can be a good choice. Even prterigion ungium can improve. I have not found association with
hepatitis C virus infection. Erosive oral lichen planus is unusual in my practice
and I do not have much experience. Regards. José Catacora
Lima-PerĂș
7:05 AM
Dear Shahbaz,
As in most inflammatory skin diseases oral steroids work best and quickly.I suspect the new monoclonals will have a significant effect on the really bad cases of generalised lichen planus especially those with oral and other mucosal involvement.
Best wishes
1:25 PM
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